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Pfizer ends trials of PF-3512676 as lung cancer treatment UPDATE


Published : Wed, 20 Jun 2007 19:15
By : Agencies
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LONDON (Thomson Financial) - Pfizer Inc said it has ended trials of PF-3512676 in combination with cytotoxic chemotherapy as a treatment for lung cancer.

The company said this includes two Phase 3 and two Phase 2 clinical trials.

Pfizer said an interim analysis of the Phase 3 trials by an independent data safety monitoring committee (DSMC) showed there was no evidence that PF-3512676 produced additional clinical efficacy over that achieved with the standard cytotoxic chemotherapy regimen alone.

'The DSMC concluded that the risk-benefit profile did not justify continuation of the trials,' the company said.

Pfizer said it licensed PF-3512676 from Coley Pharmaceutical Group Inc in 2005.

tf.TFN-Europe_newsdesk@thomson.com

wj

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