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Schering-Plough starts late-stage study


Published :
Mon, 22 Oct 2007 13:07
By : Agencies
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KENILWORTH, N.J. (AP) - Drug developer Schering-Plough Corp. said Monday it started dosing vascular disease patients with its stroke drug candidate in a late-stage study.

The thrombin receptor antagonist is an antiplatelet drug aimed at keeping platelets from sticking together. Aspirin is a common antiplatelet medicine.

The Phase III clinical program is expected to involve 30,000 patients with vascular disease. The first study will involve about 19,500 patients who have previously had a stroke.

The company said patients undergoing angioplasty and treated with the drug in an already completed Phase II clinical trial had a lower number of strokes. The Phase II study was not designed to establish the drug's effectiveness.

The company also said midstage study results showed the drug candidate did not increase a patients' risk of bleeding. Those results confirm safety results seen in previous studies, the company said.

Shares of Schering-Plough rose 86 cents, or 2.6 percent, to $33.57 in premarket trading.

Copyright 2007 Associated Press. All rights reserved. This material may not be published, broadcast, rewritten, or redistributed.




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